ICSI or IVF?

 

These two terms are very frequently mentioned during each one of your visits to the fertility clinic. Both of them imply different techniques using the same gametes, sperm and egg.

 

ICSI stands for Intra Cytoplasmic Sperm Injection. This is a technique, which takes one sperm inside a needle, and the sperm is then injected into the egg.

 

IVF stands for the In Vitro Fertilization technique, which is the placement of a sperm sample on a dish containing one or more eggs. This way the sperm will naturally penetrate de egg.

 

Both techniques are complex and require to be performed in an embryology laboratory.

 

Doctors usually have different criteria to decide if a patient goes to ICSI or IVF. Some of the criteria to do ICSI are:

 

• Poor quality sperm. This can be shown either in the quantity, motility or morphology.
• Patients over 40 years old
• Prior IVF failures
• Borderline sperm DNA fragmentation

 

Criteria to consider IVF:

 

• Good quality sperm. This has to be shown at least in all of the criteria of motility, quantity, and morphology.
• Patients under 40 years old
• Sperm DNA fragmentation under 25%

 

Your fertility specialist will let you know about the results of the analysis and the criteria you have to either undergo ICSI or IVF.

 

 

Sometimes a split case of IVF/ICSI can be performed, and in most cases where the sperm quality is borderline, or there is unexplained infertility there is a good chance of success. A study shows that performing ICSI on at least some of the oocytes will avoid unnecessary fertilization failure in patients with borderline semen (1)(2).

 

Several serious studies have not shown any difference on embryo quality obtained with ICSI or FIV. Some of them concluded: embryo quality does not seem to be influences by the mode of fertilization (IVF or ICSI) (3)...Continue reading

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